SignalChem’s targets out-perform the competition.
All activity assays were performed in-house under the same experimental conditions.

SignalChem employs the “Gold Standard” radiolabel-based kinase screening format as part of its profiling service as it provides several advantages over some of the newer technologies. In particular, the radiolabel format provides a direct measure of catalytic activity, has the highest signal-to-noise ratio and has minimal issues with compound interference.

The discovery team at SignalChem has over 30 years of combined experience in the areas of signal transduction, enzyme kinetics and high throughput screening. We are committed to delivering the highest quality products and services and have been highly successful in establishing strong partnerships with several large life science, biotech and pharmaceutical companies.

SignalChem understands the importance of discovery timelines and works to provide the profiling results within a two-week time period. A typical report includes a detailed summary of the results, graphical and numerical representation of the findings along with the original data.

Recent References:
1. Ong, CJ. et al: Small molecule agonists of SHIP1 inhibit the phosphoinositide 3-kinase pathway in hematopoietic cells. Blood 2007 May 14; Epub.